Importance: The results of the American College of Surgeons Oncology Group Z (ACOSOG Z) trial were first reported in with a. In , the ACOSOG Z trial showed equivalent survival and recurrence between sentinel lymph node biopsy (SLNB) alone versus axillary lymph node. ABSTRACT. Introduction. The ACOSOG Z trial has been described as practice-changing. The goal of this study was to determine the.
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However, these validation data have been generated in Western populations. As the socio-economic profile, life style and culture of Asian are substantially different from those of Western, and genetic backgrounds vary to some extent, it remains unclear whether results similar to those of the Z study acosog z0011 trial be achieved in a Chinese breast cancer population.
The year disease-free survival was Ten-year regional recurrence did not differ significantly between the 2 groups. Among women with T1 or T2 invasive primary breast cancer, no palpable axillary adenopathy, and 1 or acosog z0011 trial sentinel lymph nodes containing metastases, year overall survival for patients treated with sentinel lymph node dissection alone was noninferior to overall survival acosog z0011 trial those treated with axillary lymph node dissection.
Due to the significant morbidity of ALND, including paresthesias, acosog z0011 trial, seroma, and infection, judicious use of the procedure is important. The American College of Surgeons Oncology Group ACOSOG Z trial was a multicenter noninferiority study which enrolled and randomized patients with breast cancer, T disease, clinically negative axillary nodes, 1 or 2 macrometastatic nodes on SLNB, and a plan for breast conserving therapy acosog z0011 trial of lumpectomy and whole-breast radiation.
The year survival results of Z are reported here. All pts were to receive whole breast irradiation and systemic therapy.